Frankfurt grabbed an early lead when Eric Dier lost control and Daichi Kamada was set up for a close-range goal, but Harry Kane set up Son six minutes later to equalize.
England captain Kane then converted a penalty, and Son’s thunderous strike made it 3-1 before halftime.
Tuta was awarded a second yellow card for pulling Son down early in the second half, but Faride Alidou’s header made it 3-2 with three minutes remaining, giving Spurs an anxious finish.
Tottenham held on despite Kane missing a second penalty in stoppage time.
Tottenham looked like they were back to their best at moments and might have won by more, but clumsy blunders kept Frankfurt in the game.
The visitors struggled to deal with Tottenham’s assault, although goalkeeper Hugo Lloris was forced to tip over a Jesper Lindstrom attempt, and there was some desperate defense late on as Frankfurt had chances.
Son, Ryan Sessegnon, Richarlison, and Cristian Romero were among those who came close for Antonio Conte’s hosts.
It was a tense finish, but Tottenham now leads the group with two victories from four games, while Frankfurt drops to the foot of the table with four points.
Tottenham will play Sporting Lisbon on October 26th.
Frankfurt dominated early on and pressed and harried Spurs, leading to a mistake from Dier and the opening goal from Kamada, who had already come close when just failing to connect with Lindstrom’s curling cross.
But it did not take long for Tottenham to capitalise on the gaping spaces left in behind by Frankfurt.
Kane and Son were on form, linking up fluently and causing havoc as Richarlison worked tirelessly to create space for his team-mates to run into.
The efficiency of Spurs’ attacking line-up was too much for Frankfurt and it was only a matter of time before the hosts turned things around.
Kane won and converted a penalty when he was bundled over in the box by Kristijan Jakic less than 10 minutes after he had set up Son for the equaliser.
Son, who came off to a standing ovation, capped off a superb performance with a thumping volley before half-time.
Kane and Son have now linked up 50 times to score for Tottenham in all competitions and Richarlison’s addition to the squad has added further attacking threat.
The Brazilian almost set up Sessegnon with a brilliant curling cross early in the second half and was unfortunate not to score when he headed inches wide in the opening period.
Tottenham should have won comfortably, but Alidou’s late header set off a crazy few minutes in which Spurs replacement Bryan Gil missed a diving header, was fouled in the box to win a penalties, and Kane inexplicably blasted it over the bar.
The fans erupted as Tottenham pushed bodies in front of the ball to stop a late attack from the visitors, but they held on to win.
Tottenham had a good night overall, as they welcomed the return of Lucas Moura, who came in as a substitute for the first time since August due to injury.
I hate Tottenham Hotspur